Optimal Control Applied to a Dengue Model Incorporating Symptomatic, Asymptomatic, and Severe Cases With Limited Healthcare Resource
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Date
2025-10-14
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier
Abstract
dengue clinical manifestations and the insufficiency of public health infrastructure are not well understood. Accounting for these factors provides valuable insights for the effective management of the disease. This study develops a novel mathematical model for dengue fever that incorporates various clinical manifestations, constraints imposed by limited medical resources, and preventive control strategies. We computed the basic reproduction number and examined its correlation with model parameters. Dynamical analysis revealed that the model exhibits a backward bifurcation. Using numerical techniques, we investigated the influence of varying control strategies, modeled as both time-dependent and non-time-dependent functions, on epidemic dynamics. In both scenarios, we identified threshold levels of intervention and the timelines required for disease extinction. These findings underscore the complexity of dengue dynamics and highlight the necessity of tailored intervention approaches for effective disease management.
Description
This Journal article was published by Elsevier in 2025